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Course Unit Title Course Unit Code Type of Course Unit Level of Course Unit Year of Study Semester ECTS Credits
Enzymology KIM440 Elective Bachelor's degree 4 Spring 5

Name of Lecturer(s)

Prof. Dr. Yonca DUMAN
Prof. Dr. Neslihan ŞAKİ
Associate Prof. Dr. Mustafa Oğuzhan KAYA

Learning Outcomes of the Course Unit

1) Recognize the fundamental principles of enzymology
1) Recognize the fundamental principles of enzymology
2) Recognize the basic principles of enzyme kinetics
2) Recognize the basic principles of enzyme kinetics
3) Exemplify the application areas of enzymology
3) Exemplify the application areas of enzymology
4) Explain the purpose of enzyme kinetics.
4) Explain the purpose of enzyme kinetics.
5) Discuss the industrial applications of enzymological studies.
5) Discuss the industrial applications of enzymological studies.

Program Competencies-Learning Outcomes Relation

  Program Competencies
1 2 3 4 5 6 7 8 9 10 11 12
Learning Outcomes
1 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
1 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
2 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
2 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
3 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
3 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Biochemistry I

Course Contents

This course includes the structure and classification of enzymes, enzyme specificity, monomeric and oligomeric enzymes, chemical mechanisms in enzymatic reactions, the kinetics of single substrate enzymatic reactions, reversible and irreversible enzyme inhibitions, allosteric enzymes, the investigation of active site structure of enzymes, methods for studying enzymatic reactions, methods for measurement of enzymatic activity, applications of enzymology.

Weekly Schedule

1) The structure and classification of enzymes
2) Monomeric and oligomeric enzymes
3) Enzyme specificity
4) Chemical mechanisms in enzymatic reactions
5) Chemical mechanisms in enzymatic reactions
6) The kinetics of single substrate enzymatic reactions
7) Reversible enzyme inhibitions
8) Midterm examination/Assessment
9) Irreversible enzyme inhibitions
10) Allosteric enzymes
11) The investigation of active site structure of enzymes
12) Methods for studying, enzymatic reactions
13) Methods for measurement of enzymatic activity
14) Applications of enzymology
15) Applications of enzymology
16) Final examination

Recommended or Required Reading

1- Tim Bugg, Enzyme and Coenzyme Chemistry, Blackwell Science, UK., 1997.

Planned Learning Activities and Teaching Methods

1) Lecture
2) Lecture
3) Question-Answer
4) Question-Answer
5) Discussion
6) Discussion
7) Drill and Practice
8) Drill and Practice
9) Problem Solving
10) Problem Solving


Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade

40%

Contribution of Final Examination to Course Grade

60%

Total

100%

Language of Instruction

English

Work Placement(s)

Not Required