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Artificial Enzymes

Chemistry

Faculty of Arts and Scıences
First Cycle (Bachelor's Degree)
Course Unit Title Course Unit Code Type of Course Unit Level of Course Unit Year of Study Semester ECTS Credits
Artificial Enzymes KIM431 Elective Bachelor's degree 4 Fall 5

Name of Lecturer(s)

Prof. Dr. Yonca DUMAN
Prof. Dr. Neslihan ŞAKİ
Associate Prof. Dr. Mustafa Oğuzhan KAYA

Learning Outcomes of the Course Unit

1) Recognize active sides of enzymes
1) Recognize active sides of enzymes
1) Recognize active sides of enzymes
1) Recognize active sides of enzymes
2) Define the cyclodextrin based artificial enzymes
2) Define the cyclodextrin based artificial enzymes
2) Define the cyclodextrin based artificial enzymes
2) Define the cyclodextrin based artificial enzymes
3) Identify catalytical anticors
3) Identify catalytical anticors
3) Identify catalytical anticors
3) Identify catalytical anticors
4) Recognize protein based artificial enzymes
4) Recognize protein based artificial enzymes
4) Recognize protein based artificial enzymes
4) Recognize protein based artificial enzymes
5) Sytnhesize artificial enzymes
5) Sytnhesize artificial enzymes
5) Sytnhesize artificial enzymes
5) Sytnhesize artificial enzymes

Program Competencies-Learning Outcomes Relation

  Program Competencies
1 2 3 4 5 6 7 8 9 10 11 12
Learning Outcomes
1 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
1 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
1 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
1 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
2 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
2 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
2 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
2 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
3 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
3 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
3 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
3 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

yok

Course Contents

This course includes active sides of enzymes, artificial enzyme designs (cyclodextrins, cyclodextrins based enzyme models; calixarenes, calixarenes based enzyme models), cucurbiturils, evolution of synthetic polymers with enzyme-like catalytic activities, catalytic antibodies, and protein-based artificial enzymes.

Weekly Schedule

1) Introduction to Enzymes and Catalysis
2) Active side of Enzymes
3) Mechanisms in enzymatic reactions
4) Cyclodextrins
5) Calixarenes
6) Cucurbiturils
7) Cyclodextrins as Artificial Enzyme Models-I
8) Midterm examination/Assessment
9) Cyclodextrins as Artificial Enzyme Models-II
10) Calixarenes as Artificial Enzyme Models
11) Synthetic Polymers with Enzyme-like Catalytic Activities
12) Mimicking Enzymes with Antibodies
13) Mimicking Enzymes with Antibodies
14) Protein-based Artificial Enzymes
15) Protein-based Artificial Enzymes
16) Final examination

Recommended or Required Reading

1- R. Breslow, Artificial Enzymes

Planned Learning Activities and Teaching Methods

1) Lecture
2) Lecture
3) Question-Answer
4) Question-Answer
5) Discussion
6) Discussion
7) Drill and Practice
8) Drill and Practice
9) Problem Solving
10) Problem Solving


Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade

40%

Contribution of Final Examination to Course Grade

60%

Total

100%

Language of Instruction

English

Work Placement(s)

Not Required