| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Biochemistry III | KIM436 | Elective | Bachelor's degree | 4 | Spring | 5 |
Name of Lecturer(s)
Prof. Dr. Yonca DUMAN
Prof. Dr. Neslihan ŞAKİ
Associate Prof. Dr. Mustafa Oğuzhan KAYA
Learning Outcomes of the Course Unit
1) Recognize the genes and chromosoms.
2) Describe the DNA metabolism (replication, repairing and recombination)
3) Describe the RNA metabolism (DNA dependent RNA synthesis, RNA processing, RNA dependent RNA and DNA synthesis)
4) Discuss the protein metabolism (Genetic code, Protein synthesis, Protein targeting)
5) Recognize the gene expression and it's regulation (Regulation of gene expression in prokaryotes, Regulation of gene expression in eukaryotes)
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||||||||||
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | ||
| Learning Outcomes | |||||||||||||
| 1 | High | High | High | High | High | High | High | High | High | High | High | High | |
| 2 | High | High | High | High | High | High | High | High | High | High | High | High | |
| 3 | High | High | High | High | High | High | High | High | High | High | High | High | |
| 4 | High | High | High | High | High | High | High | High | High | High | High | High | |
| 5 | High | High | High | High | High | High | High | High | High | High | High | High | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Biochemisry I, Biochemistry II
Course Contents
This course includes genes and chromosomes, DNA supercoiling, chromatin and nucleolid structure, DNA metabolism: DNA replication, DNA repair and DNA recombination, RNA metabolism: DNA dependent RNA synthesis, RNA processing, RNA dependent RNA and DNA synthesis, Protein metabolism: genetic code, protein synthesis, protein targeting, gene expression and its regulation: regulation of gene expression in prokaryotes, regulation of gene expression in eukaryotes, principles and applications of recombinant DNA technology.
Weekly Schedule
1) Genes and chromosomes2) DNA supercoiling, Chromatin and nucleolid structure
3) DNA metabolism: DNA replication
4) DNA metabolism: DNA repair
5) DNA metabolism: DNA recombination
6) RNA metabolism: DNA dependent RNA synthesis
7) RNA metabolism: RNA processing, RNA dependent RNA and DNA synthesis
8) Midterm examination/Assessment
9) Protein metabolism: Genetic code
10) Protein metabolism: Protein synthesis
11) Protein metabolism: Protein targeting
12) Gene expression and its regulation
13) Regulation of gene expression in prokaryotes
14) Regulation of gene expression in eukaryotes
15) Principles and applications of recombinant DNA technology
16) Final examination
Recommended or Required Reading
1- D. L. Nelson & M. M. Cox, Principles of Biochemistry, 4th Ed., Worth Publishers, USA., 2005.
2- D. Voet, J. G. Voet, Biochemistry, 3rd Ed., John Wiley & Sons, USA., 2004
3- Geoffrey L. Zubay, Biochemistry, 4th Ed., Mc Graw Hill, USA., 1998.
Planned Learning Activities and Teaching Methods
1) Lecture
2) Lecture
3) Lecture
4) Lecture
5) Question-Answer
6) Question-Answer
7) Question-Answer
8) Question-Answer
9) Discussion
10) Discussion
11) Discussion
12) Discussion
13) Drill and Practice
14) Drill and Practice
15) Drill and Practice
16) Drill and Practice
17) Problem Solving
18) Problem Solving
19) Problem Solving
20) Problem Solving
Assessment Methods and Criteria
Contribution of Midterm Examination to Course Grade |
30% |
|---|---|
Contribution of Final Examination to Course Grade |
70% |
Total |
100% |
Language of Instruction
English
Work Placement(s)
Not Required