Kocaeli University / European Credit Transfer System (ECTS)

Name of Lecturer(s)

Prof. Dr. Semil Selcen GÖÇMEZ

Learning Outcomes of the Course Unit
Program Competencies-Learning Outcomes Relation

Learning Outcomes of the Course Unit

1) Explains the characteristics of drugs
2) Explains the entrance ways, distribution and elimination of drugs
3) Explains the biotransformation mechanism of drugs.
4) Explains the drug receptors and ligands
5) Expalins the drug interactions
6) Defining drug effect mechanisms Defining drug receptors and second messengers
7) Explains the toxic effects of drugs, drug allergy and types of allergic reaction.
8) Defines the general principals of antibiotic usage.
9) Explains the usage of antibiotics in bacterial infections and their alternatives.
10) Explains the pharmacology of antineoplastic and antituberculosis drugs.
11) Explains the colinergic system and mechanism of drugs effecting this system.
12) Explains the sempatic system and the mechanism of drugs effecting this system.
13) Defines the pharmacological approach to hypertension.
14) Defines the pharmacological approach to congestive heart failure and arytmia.
15) Defines the pharmacological approach to ischemic heart disorder and dislipidemia.
16) Explains the rules of prescribing drugs.

Program Competencies-Learning Outcomes Relation

		Program Competencies
		1	2	3	4	5	6
Learning Outcomes
	1	Low	No relation	No relation	No relation	No relation	No relation
	2	Low	No relation	No relation	No relation	No relation	No relation
	3	Low	No relation	No relation	No relation	No relation	No relation
	4	Middle	No relation	No relation	No relation	No relation	No relation
	5	Middle	No relation	No relation	Low	Low	No relation
	6	High	No relation	No relation	No relation	No relation	No relation
	7	Middle	No relation	No relation	No relation	Low	Low
	8	High	No relation	Middle	No relation	Middle	No relation
	9	Middle	No relation	Middle	No relation	Middle	No relation
	10	Middle	No relation	No relation	No relation	No relation	No relation
	11	Middle	No relation	No relation	No relation	Low	No relation
	12	Middle	No relation	No relation	No relation	No relation	No relation
	13	Middle	No relation	No relation	No relation	Low	No relation
	14	Middle	No relation	No relation	No relation	Middle	No relation
	15	High	No relation	Middle	No relation	Middle	No relation
	16	High	No relation	High	High	High	High

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Physiology, Cardiology, İnfection diseases

Course Contents

A. General Pharmacology 1. Introduction to pharmacology 2. Drug administration routes and pharmaceutical types 3. Pharmacokinetic phases 3.1. Absorbtion of drugs 3.2. Distribution of drugs 3.3. Metabolisation of drugs 3.4. Elimination of drugs 4.Pharmacodynamic phases 5.Pharmacokinetic and pharmacodynamic interactions 6.Drug action mechanisms 7.Toxic effects of drugs B. Chemotherapeutic agents 1.Introduction to Chemotherapeutics 2.Penicillins, Cephalosporins, Beta-lactam antibiotics 3.Aminoglucosidos, tetracyclines,lincosamids, macrolides 4.Fluoroquinolones, Sulfonamides, Trimethopirim 4.Antianaerobics C. Otonomic nervous system pharmacology 1.Introduction to otonomic nervous system 2.Sympathomimetics 3.Sympatholitics 4.Parasympathomimetics 5.Parasympatholitics 6.Ganglion stimulants and inhibitors D. Cardiovasculer system pharmacology 1.Drugs used in conjestive heart failure 2.Antianginal drugs 3.Antiarrhythmic drugs 4.Therapy of hypertension 5.Hypolipidemic drugs 6.Anticoagulants and drugs used to stop bleeding E. Respiratory system pharmacology 1. Antitussives and expectorants 2. Bronchodilators 3. Drugs used in the therapy of asthma and chronic obstructive lung disease F. Renal system pharmacology 1. Drugs affecting on renin-angiotensin-aldostrone system 2. Drugs used in the therapy of liquid-electrolyte balance disorders 2. Drugs used in the therapy of acide-base balance disorders G. Central nervous system pharmacology 1. General anesthetics, local anesthetics 2. Narcotic analgesics, nonsteroidal antiinflammatory analgesics 3. Hypnosedatives, Antidepressants and antimanics, Antipsychotics H. Gastrointestinal system pharmacology 1. Emetics and antiemetics 2. Antidiarrheal drugs 3. Laxatives and purgatives 4. Drugs used in the therapy of peptic ulcus I. Endocrin system pharmacology 1. Introduction to endocrin system pharmacology 2. Hypothalamus and hypophyseal hormones 3. Gonadal hormones and drugs 4. Oral contraseptive drugs J. Autocoids 1. Amine structured autocoids (Histamine and serotonin) 2. Peptide structured autocoids (Angiotensine and kinines) 3. Lipide structured autocoids (Prostaglandins and leucotrienes) K. Drugs used during pregancy

Weekly Schedule

1) general principles of pharmacology
2) Pharmacokinetics of drugs
3) drug metabolism
4) pharmacodynamic
5) drug interaction
6) drug mechanism of action
7) toxic effects of drugs, general principles of chematherapeutics
8) beta lactam antibiotics
9) exam
10) other antibiotics
11) antineoplastic drugs, treatment of tuberculosis
12) Autonomic nervous system pharmacology
13) antihypertensive drugs, treatment of congestive heart disease
14) antiarrythmic drugs, hipolipidemic drugs
15) rules of drug prescription
16) exam

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice
5) Group Study
6) Self Study

Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade	20%
Contribution of Final Examination to Course Grade	80%
Total	100%

Language of Instruction

Work Placement(s)

Not Required

Course Unit Title	Course Unit Code	Type of Course Unit	Level of Course Unit	Year of Study	Semester	ECTS Credits
Pharmacology I		Elective	Bachelor's degree	2	Fall	2