Advanced Biochemistry I
Chemistry
Institute of Natural and Applied Sciences
Second Cycle (Master's Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Advanced Biochemistry I | KIM515 | Elective | Master's degree | 1 | Fall | 8 |
Name of Lecturer(s)
Prof. Dr. Yonca DUMAN
Prof. Dr. Neslihan ŞAKİ
Associate Prof. Dr. Mustafa Oğuzhan KAYA
Learning Outcomes of the Course Unit
1) Recognize of protein structure and folding
2) Associate of properties of structure-function of proteins
3) Identify of protein stability and denaturation
4) Correlate of DNA and protein
5) Recognise of DNA of procaryots and eucaryots
6) Recognize of immun system
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||||
| 1 | 2 | 3 | 4 | 5 | 6 | ||
| Learning Outcomes | |||||||
| 1 | High | High | High | High | High | High | |
| 2 | High | High | High | High | High | High | |
| 3 | High | High | High | High | High | High | |
| 4 | High | High | High | High | High | High | |
| 5 | High | High | High | High | High | High | |
| 6 | High | High | High | High | High | High | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Biochemistry I & II
Course Contents
Basic structural principles in proteins, Motifs of protein structure, Alpha domain structures in proteins, Alpha/Beta structures in proteins, Beta structures in proteins, Protein folding and flexibility, The kinetics and thermodynamics of protein folding, Protein function-structure relationships, Conformational changes on protein denaturation, Molecular concepts of protein stability, Fundamentals of protein engineering, DNA-Protein relationships, DNA recognition mechanisms in prokaryotes and eukaryotes, Immune system and immunuglobulins.
Weekly Schedule
1) Basic structural concepts in proteins2) Motifs of protein structure
3) Alpha domains structure in proteins
4) Alpha/beta strucures in proteins
5) Beta structures in proteins
6) Protein folding and flexibility
7) Relation of structure/function in proteins
8) Mid-term exam
9) Structural changes at protein denaturation
10) Molecular concepts at protein stability
11) DNA-protein relations
12) DNA recognation mechanisms at procaryote and eucaryote
13) Immune and immonoglobulins
14) Seminar
15) Seminar
16) Final exam
Recommended or Required Reading
1- D. L. Nelson & M. M. Cox, Principles of Biochemistry, 4th Ed., Worth Pub., USA., 2005
2- D. Voet, J. G. Voet, Biochemistry, John Wiley & Sons, 3rd USA., 2004
3- D. Voet, J. G. Voet, Biochemistry, John Wiley & Sons, 3rd USA., 2004
4- D. L. Nelson & M. M. Cox, Principles of Biochemistry, 4th Ed., Worth Pub., USA., 2005
5- Geoffrey L. Zubay, Biochemistry, 4th Ed., Mc Graw Hill, USA., 1998.
6- Geoffrey L. Zubay, Biochemistry, 4th Ed., Mc Graw Hill, USA., 1998.
Planned Learning Activities and Teaching Methods
1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice
5) Group Study
6) Problem Solving
Assessment Methods and Criteria
Contribution of Midterm Examination to Course Grade |
40% |
|---|---|
Contribution of Final Examination to Course Grade |
60% |
Total |
100% |
Language of Instruction
Turkish
Work Placement(s)
Not Required