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Course Unit Title Course Unit Code Type of Course Unit Level of Course Unit Year of Study Semester ECTS Credits
General Physiology BMM502 Elective Master's degree 1 Spring 7

Name of Lecturer(s)

Prof. Dr. Deniz ŞAHİN
Research Assistant Hatice ASRİ

Learning Outcomes of the Course Unit

1) Acquire an understanding about the principles of human physiology and professional lives and applies this information
2) Explain the general concept of homeostasis and physiological systems and the principles of positive and negative feedback
3) Write Nernst equation and explain chemical and electrical driving forces using the equation causing an ion movement
4) Define diffusion, facilitated diffusion, secondary active transport and active transport properties of the primary and compare them to each other and summarize the properties of ion channels
5) Distinguish electrotonic conduction, action potential conduction and conduction properties of punctuated anf phases of the action potential (depolarization, transcendence, repolarization, hyperpolarization) and explain the role of these channels
6) Describe the general principles of heart and smooth muscle skeleton
7) Describe the properties of a neuron electrical activity in different regions
8) Recognize voltage-gated Na ,, K , and Ca2 , channels and explain the role of the action potential
9) List phases of the action potential (depolarization, transcendence, repolarization, hyperpolarization) and expound the role of these channels
10) Circulatory System Physiology: Learns the stimulation and conduction system of the heart, the electrocardiogram, the cardiac cycle, the veins and arterial blood pressure, the factors affecting arterial blood pressure, the characteristics of biopotentials that are the source of the ECG.
11) Respiratory System Physiology: Learns the basic functions of the respiratory system. Comprehends the volumes and capacities measured in Spirometry ( Procedure, Normal Values, and Test Results)
12) Urinary System Physiology: Learns the structure of nephrons and urine formation, Glomerul filtration rate and clearance concept, Juxtaglomerular apparatus and renin-angiotensin system. Can associate with dialysis systems.
13) Learns the basic mechanisms, structural and functional properties of the nervous and endocrine systems in controlling other systems of the living organism.
14) Learns pituitary gland and hormones, thyroid gland and hormones, adrenal cortex hormones, adrenal medulla and catecholamine secretion, sex hormones, pancreatic hormones, hormones effective on calcium metabolism and related diseases.

Program Competencies-Learning Outcomes Relation

  Program Competencies
1 2 3 4 5 6 7 8 9
Learning Outcomes
1 Middle Low Low Low Middle Middle Low Middle Middle
2 No relation No relation No relation Low No relation No relation Low Low No relation
3 No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 Middle Middle Middle Middle Middle Middle Middle Middle Middle
6 Middle Middle Middle Middle Middle Middle Middle Middle Middle
7 Middle High Middle Middle Middle Middle Middle Middle High
8 Middle Middle Middle Middle Middle Middle Middle Middle High
9 Middle Middle Low Middle Middle High Middle Middle High
10 Middle Middle Middle Middle Middle Middle High Middle Middle
11 High No relation No relation No relation No relation No relation No relation No relation No relation
12 No relation No relation No relation No relation No relation No relation No relation No relation No relation
13 No relation No relation No relation No relation No relation No relation No relation No relation No relation
14 No relation No relation No relation No relation No relation No relation No relation No relation No relation

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Anotomy

Course Contents

This course equips candidates with in-depth knowledge on functioning of all organs and systems, mechanisms and regulations, basic respiratory, circulatory, excretory, digestive system and the central nervous system, general principles and sensory physiology.

Weekly Schedule

1) The Concept of Homeostasis; Structure and Function of Cell Membrane and Missions of Cell Organelles
2) Body Fluids, Ion Channels and Cell Membrane Transport Mechanisms
3) Excitable Tissues
4) Synaptic Transmission and Nerve Muscle Junction
5) Muscle Physiology: Skeletal Muscle, Cardiac Muscle, Smooth Muscle
6) Biological Potentials and Recording Methods: EEG, EMG, ECG
7) Nervous System I: Structure of Neurons, Regions of Synapses and Synaptic Transmission Link, Structure and Functions of the Central Nervous System
8) Midterm Examination/Assessment
9) Nervous system II: Peripheral Nervous System and Autonomic Nervous System Functions, Reflexes, Sense of Structure of the Eye and Vision, Ear, Hearing and Sense of Balance
10) Midterm Exam
11) Endocrine System: Pituitary Gland and Its Hormones, Thyroid Gland Hormones, Adrenal Cortex Hormones, Sex Hormones, Pancreatic Hormones and Calcium Metabolism of Hormones
12) Blood Physiology: Blood Cells, Bleeding and Blood Clotting Mechanism
13) Physiology of Circulatory System: Heart Warning and Messaging System, Formation of Cardiac Cycle and Heart Sounds, Peripheral Circulation and Arterial Blood Pressure, Pulse, Arrhythmias and Hypertension
14) Physiology of Respiratory System
15) Urinary System Physiology and Physiology of Digestive System
16) Final Examination

Recommended or Required Reading

1- Guyton Tıbbi Fizyoloji
2- Ders Notları ve ilgili konuları açıklayıcı linkler Örneğin; https://www.khanacademy.org/science/biology/membranes-and-transport

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Discussion
4) Demonstration
5) Group Study
6) Simulation
7) Self Study
8) Problem Solving


Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade

40%

Contribution of Final Examination to Course Grade

60%

Total

100%

Language of Instruction

Turkish

Work Placement(s)

Not Required