Kocaeli University / European Credit Transfer System (ECTS)

Name of Lecturer(s)

Prof. Dr. Mehmet Doğan GÜLKAÇ
Prof. Dr. Murat KASAP

Learning Outcomes of the Course Unit
Program Competencies-Learning Outcomes Relation

Learning Outcomes of the Course Unit

1) Explain the history of cytogenetic techniques
2) Explain the application and usage of cytogenetic techniques in medicine
3) Recognize the structure and chemistry of chromosome and chromatin
4) Define cytogenetic methods
5) Compare cytogenetics methods and techniques

Program Competencies-Learning Outcomes Relation

Program Competencies

Learning Outcomes

Middle

No relation

Middle

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Sitogenetik ve Teknikler

Course Contents

In this course, candidates are provided with profound knowledge on chemistry of chromosome, structure of chromosome, its parts and functions, chromosome movement, crossing-over and formation of chiasma, dominancy and recessivity, structural and numerical aberrations of chromosome, determination of sex, karyotype, karyotype evolution, definition of human chromosome, chromosomal abnormalities in human and genetic counseling

Weekly Schedule

1) Chemistry of Chromosome
2) Structure of Chromosome, its Parts and Functions
3) Structure of Chromosome, its Parts and Functions
4) Chromosome Movement
5) Crossing-over and Formation of Chiasma
6) Dominancy and Recessivity
7) Structural and Numerical Aberrations of Chromosome
8) Midterm Examination/Assessment
9) Determination of Sex
10) Karyotype
11) Evolution of Karyotype
12) Definition of Human Chromosome
13) Chromosomal Abnormalities in Human
14) Genetic Counseling
15) Genetic Counseling
16) Final Examination

Recommended or Required Reading

1- Verma & Arvind Babu., Ram S., Human Chromosomes. Principles and Techniques, McGraw-Hill Inc., 1995
2- Nussbaum, Roderick R. McInnes and Huntington F. Willard. W.B. , Thompson & Thompson Genetıcs in Medıcıne, Robert L. Saunders Company, 2001
3- Michael Connor & Malcolm Ferguson-Smith., Essential Medical Genetics, Blackwell Science Ltd. Fifth Edition, 1997
4- http://www.ucl.ac.uk/~ucbhjow/bmsi/bmsi 7.html
5- http://members.aol.com/chrominfo/index.htm
6- http://www.vivo.colostate.edu/hbooks/genetics/medgen/chromo/index.html
7- https://www.ksu.edu/wgrc/Protocols/Cytogenetics/staining.html

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Discussion

Assessment Methods and Criteria

Contribution of Semester Studies to Course Grade

50%

		Number	Percentage
Semester Studies	Midterm Examination	1	50%
Semester Studies	Laboratory	14	50%

Contribution of Final Examination to Course Grade

50%

Total

100%

Language of Instruction

Turkish

Work Placement(s)

Not Required

Course Unit Title	Course Unit Code	Type of Course Unit	Level of Course Unit	Year of Study	Semester	ECTS Credits
Cytogenetics and Techniques In Cytogenetics	TBG509	Elective	Master's degree	1	Fall	6