Advanced Cell and Stem Cell Biology
Stem Cell and Tissue Regeneration
Institute of Health Sciences
Second Cycle (Master's Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Advanced Cell and Stem Cell Biology | KHT532 | Elective | Master's degree | 1 | Spring | 7 |
Name of Lecturer(s)
Prof. Dr. Yusufhan YAZIR
Assistant Prof. Dr. Zehra Seda HALBUTOĞULLARI
Learning Outcomes of the Course Unit
1) To learn basic concepts in stem cell biology
2) To learn self-renewal mechanisms and cell cycle regulators in stem cells
3) Identification of embryonic stem cells, identification of specific gene expressions, epigenetic properties, examination of renewal and differentiation mechanisms
4) Fundamentals of reprogramming of somatic cells and learning of induced pluripotent stem cell concept
5) Be able to define adult stem cells
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||||
| 1 | 2 | 3 | 4 | 5 | 6 | ||
| Learning Outcomes | |||||||
| 1 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 2 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 3 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 4 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 5 | No relation | No relation | No relation | No relation | No relation | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Stem Cell Disease
Course Contents
Stem cells and types of these cells, isolation and clinical practice, ethical debates and legal regulations in stem cell applications, with molecular biology techniques will be more comprehensive knowledge of stem cell biology studies
Weekly Schedule
1) Introduction to stem cell biology and basic concepts2) Self-renewal mechanisms in stem cells
3) Cell cycle regulators in stem cells
4) Identification of embryonic stem cells, identification of specific gene expressions, epigenetic properties, examination of renewal and differentiation mechanisms
5) Reprogramming bases of somatic cells, identification of induced pluripotent stem cell characteristics
6) Identification of adult stem cells
7) Hematopoietic stem cells
8) Quiz
9) Mesenchymal stem cells
10) Amniotic fluid, cord blood, peripheral blood stem cells
11) Properties of skeletal and cardiac muscle stem cells
12) Stem cells in the nervous system, stem cell applications in neurodegenerative diseases 49/5000 Root cells in the nervous system, stem cell applications in neurodegenerative diseases 49/5000 Features of skeletal muscle and heart stem cells
13) Basic features of epidermal / skin stem cells
14) Identification of stem cells in cancer
15) Cell therapy, stem cell applications in the clinic and ethical discussions
16) Final exam
Recommended or Required Reading
1- Essentials of Stem Cell Biology. R. Lanza, J. Gearhart, B. Hogan, D. Melton, R.Pederson, E.D. Thomas, J.Thomson, I. Wilmut. Academic Press.
2- Stem cells: scientific progress and future research directions. National Institutes of Health. November 2004, University Press of the Pacific. ISBN: 978-1-4102-1896-4
3- Biology of Stem Cells and the Molecular Basis of the Stem State. Dov Zipori, 2009, Humana Press, Heidelberg, ISBN: 978-1-60761-130-1
Planned Learning Activities and Teaching Methods
1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice
5) Brain Storming
Assessment Methods and Criteria
Contribution of Semester Studies to Course Grade |
40% |
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Contribution of Final Examination to Course Grade |
60% |
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Total | 100% | |||||||||||
Language of Instruction
Turkish
Work Placement(s)
Not Required