Enzyme and Coenzyme Chemistry
Chemistry
Institute of Natural and Applied Sciences
Third Cycle (Doctorate Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Enzyme and Coenzyme Chemistry | KIM605 | Elective | Doctorate degree | 1 | Fall | 8 |
Name of Lecturer(s)
Prof. Dr. Yonca DUMAN
Prof. Dr. Neslihan ŞAKİ
Associate Prof. Dr. Mustafa Oğuzhan KAYA
Learning Outcomes of the Course Unit
1) Identify of Structure and function and Control of enzyme activity
2) Analysis of Methods for studying enzymatic reactions
3) Explain of Enzymatic redox chemistry and Enzymatic carbon-carbon bond formation,
4) Recognize of Interactions by active site directed inhibitors and Non-enzymatic biological catalysis.
5) Isolate of intermedia pruduct of enzymatic reactions.
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||
| 1 | 2 | 3 | 4 | ||
| Learning Outcomes | |||||
| 1 | High | High | High | High | |
| 2 | High | High | High | High | |
| 3 | High | High | High | High | |
| 4 | High | High | High | High | |
| 5 | High | High | High | High | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Enzymology
Course Contents
Function and structure of enzymes, control of enzyme activity, chemicial mechanism of enzymatic catalysis, defination of intermedia product at enzymatic reactions, chemistry of enzymatic redox, enzymatic formation of C-C bound, enzymatic subtition and elimination reactions, enztmatic isomerisation reactions.
Weekly Schedule
1) Structure and function of enzymes2) Control of enzyme activity
3) Chemical mechanisms of enzymatic catalysis
4) Reading an article
5) Methods of working enzymatic reactions
6) Determination of intermediates in enzymatic reactions
7) Stereochemistry of enzymatic reactions
8) Midterm
9) Hydrolytic and group transfer reactions catalyzed by enzymes
10) Enzymatic redox chemistry,
11) Enzymatic carbon-carbon bond formation,
12) Interactions with irreversible inhibitors directed to the enzyme active site
13) Reading an article
14) Reading an article
15) Reading an article
16) Exam
Recommended or Required Reading
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Contribution of Midterm Examination to Course Grade |
30% |
|---|---|
Contribution of Final Examination to Course Grade |
70% |
Total |
100% |
Language of Instruction
Turkish
Work Placement(s)
Not Required