Protecting Groups In Organic Chemistry

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Organic Chemistry 1

Course Contents

Introduction; The protection of alcohols; The protection of aldehydes and ketones; The protection of carboxylic acids; The protection of the amino group; The protection of thiols; The protection of unsaturated systems; Some experimental methods; Some common abbreviations for protecting groups and reagents

Weekly Schedule

1) Introduction to protecting group chemistry
2) Function of protecting groups in Organic Chemistry
3) Protecting of hydroxyl groups
4) Deprotecting of hydroxyl groups
5) Protecting of carbonyll groups
6) Deprotecting of carbonyl groups
7) Protecting of carboxyl groups
8) Visa
9) Deprotecting of carboxyl groups
10) Protecting of amino groups
11) Deprotecting of amino groups
12) Protecting of thiol groups
13) Deprotecting of thiol groups
14) Protecting and deprotecting of other founctional groups
15) Reactivity and chemicals
16) Final

Recommended or Required Reading

1- James R. Hanson, Protecting Groups in Organic Synthesis (Postgraduate Chemistry Series), 1999
2- T.W. Greene, P. G. M. Wuts , The Role of Protective Groups in Organic Synthesis, Wiley 2006
3- P. Kocienski, Protecting Group Foundations of Organic Chemistry-3rd Ed.
4- Cavit UYANIK, Organik Kimya, 11. baskı, Literatür, 2016
5- G. Solomon, Organic Chemistry, 11th edition, Wiley, 2014

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Discussion
4) Modelling
5) Brain Storming
6) Self Study

Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade	40%
Contribution of Final Examination to Course Grade	60%
Total	100%

Language of Instruction

Turkish

Work Placement(s)

Not Required