Organic Sterochemistry
Chemistry
Institute of Natural and Applied Sciences
Third Cycle (Doctorate Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Organic Sterochemistry | KIM617 | Elective | Doctorate degree | 1 | Fall | 8 |
Name of Lecturer(s)
Prof. Dr. Cavit UYANIK
Prof. Dr. Mehmet YILMAZ
Associate Prof. Dr. Selahaddin GÜNER
Learning Outcomes of the Course Unit
1) Make the definition and naming of macrocyclic compounds
2) Explain how macrocyclic compounds are able to synthesize
3) Identify the crown ethers and their properties
4) Describe thia crown ethers
5) Explain the aza crown ethers
6) Explain the macrocyclic-ion interaction
7) Make the synthesises and naming of cryptands and their complexes
8) Explain the calixarens, cavitands and catenens
9) Describe the kinetics and thermodynamic of the interaction of macrocyclic-Ion
10) List the applications of macrocyclic compounds
11) Define the basic concepts of supramolecular chemistry
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||
| 1 | 2 | 3 | 4 | ||
| Learning Outcomes | |||||
| 1 | High | High | High | High | |
| 2 | High | High | High | High | |
| 3 | High | High | High | High | |
| 4 | High | High | High | High | |
| 5 | No relation | No relation | No relation | No relation | |
| 6 | High | High | High | High | |
| 7 | High | High | High | High | |
| 8 | High | High | High | High | |
| 9 | High | High | High | High | |
| 10 | High | High | High | High | |
| 11 | High | High | High | High | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
organic
Course Contents
Chirality, Structure of Molecules, Isomerisms, Enantiomers, Symmetry Plane and Mirror Image, Optical Activity, Diastereomers and Stereoisomers, Sterochemical Discriptors: D and L Notation, R and S Notation, á and â Notation, Axial and Equatorial Positions, Endo and Exo Nomenclature, Erythro and Threo Nomenclature, Syn-anti Nomenclature, Cis-Trans Nomenclature, E, Z Nomenclature, Eclipced and Staggered Conformations, Gauche and Anti Conformations, Conformation of Alkanes and Cycloalkanes, Conformational Analysis, Anomeric Effects, Stereochemical Control Asymmetric Sythesis with Chiral Subsrate, Conformational Analysis with NMR Spectroscopy.
Weekly Schedule
1) Chirality, Structure of Molecules, Isomerisms, Enantiomers, Symmetry Plane and Mirror Image, Optical Activity,2) Diastereomers and Stereoisomers, Sterochemical Discriptors: D and L Notation, R and S Notation
3) Axial and Equatorial Positions, Endo and Exo Nomenclature
4) Erythro and Threo Nomenclature, Syn-anti Nomenclature, Cis-Trans Nomenclature, E, Z Nomenclature
5) Eclipced and Staggered Conformations, Gauche and Anti Conformations,
6) Eclipced and Staggered Conformations, Gauche and Anti Conformations,
7) Conformation of Alkanes and Cycloalkanes, Conformational Analysis
8) midterm
9) Conformational Analysis, Anomeric Effects,
10) Conformational Analysis, Anomeric Effects,
11) Conformational Analysis, Anomeric Effects,
12) Stereochemical Control Asymmetric Sythesis with Chiral Subsrate
13) Stereochemical Control Asymmetric Sythesis with Chiral Subsrate
14) Conformational Analysis with NMR Spectroscopy.
15) Conformational Analysis with NMR Spectroscopy.
16) Final examination
Recommended or Required Reading
1- Concepts and Terminology in Organic Stereochemistry M. Kaloustian
2- Organic Stereochemistry: Experimental and Computational Methods, First Edition. Hua-Jie Zhu.
3- Introduction to Stereochemistry (2002, Dover Publications) - Mislow, Kurt
Planned Learning Activities and Teaching Methods
1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice
5) Modelling
6) Simulation
7) Problem Solving
Assessment Methods and Criteria
Contribution of Midterm Examination to Course Grade |
50% |
|---|---|
Contribution of Final Examination to Course Grade |
50% |
Total |
100% |
Language of Instruction
Turkish
Work Placement(s)
Not Required