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Genetics and Developmental Physiology

Medicine

Faculty of Medicine
First Cycle (Bachelor's Degree)
Course Unit Title Course Unit Code Type of Course Unit Level of Course Unit Year of Study ECTS Credits
Genetics and Developmental Physiology TIP104 Compulsory Bachelor's degree 1 9

Name of Lecturer(s)

Prof. Dr. Gürler AKPINAR
Prof. Dr. Belgin BAMAÇ
Prof. Dr. Fatma BUDAK
Prof. Dr. Meltem Özlen DİLLİOĞLUGİL
Prof. Dr. Emel ERGÜL
Prof. Dr. Serdar FİLİZ
Prof. Dr. Süheyla GONCA
Prof. Dr. Mehmet Doğan GÜLKAÇ
Prof. Dr. Murat KASAP
Prof. Dr. Sema Aşkın KEÇELİ
Prof. Dr. Fetiye KOLAYLI
Prof. Dr. Hale MARAL KIR
Prof. Dr. MELDA YARDIMOĞLU YILMAZ
Prof. Dr. Yusufhan YAZIR
Prof. Dr. Zeki YUMUK
Associate Prof. Dr. Aslıhan AKPINAR
Associate Prof. Dr. Fatma Ceyla ERALDEMİR
Associate Prof. Dr. Banu İSKENDER İZGİ
Assistant Prof. Dr. Erdener BALIKÇI
Assistant Prof. Dr. Zehra Seda HALBUTOĞULLARI

Learning Outcomes of the Course Unit

1) Explains the structure of microorganism, genetic properties, reproductive patterns and their classification.
2) Interprets the general characteristics, classification, replication and genetic changes in the structure of viruses.
3) Explains the general properties of fungi, parasites and their importance in human health.
4) Solves the metabolism of amino acids, fatty acids, cholesterol, DNA, glycoproteins and proteoglycans.
5) Interprets the mechanisms of genomic evolution and the use of FISH diagnostic methods.
6) Differentiates the role of human chromosome structure, function, karyotyping, CGH and FISH techniques in understanding genetic diseases.
7) Knows the mutations and carcinogens and solves the effects of these factors on mutagenesis and carcinogenesis.
8) Knows the genetic diseases that may arise as a result of and aberrations and detailed interprets of how genetic problems should be approached.
9) Explains the cultural evolution and biological evolution of Homo sapiens with the general concept of evolution and the milestones of human evolution.
10) Knows how to isolate DNA, RNA and protein from human lymphocytes. Understands mutation screening, genotyping and PCR methods and the basics of individualized treatment options.
11) Understands the structure and properties of myoglobin and hemoglobin and defines the general principles of the biochemical mechanisms of diseases.
12) Defines the developmental and structural changes of the embryo, explain the formation of the germ disc, differentiation of the germ layers, congenital disorders and their causes.
13) Knows how to isolate DNA, RNA and protein from human lymphocytes. Understands the basics of personalized treatment options by learning mutation screening, genotyping and PCR methods.
14) Comprehends about "Relationships with values, attitudes and behaviors", the interrelationships of interest, love, affinity, aggression, violence.
15) Acquires knowledge concerning the development and differentiation process of the organs, knows the classification and the basic properties of various microorganisms, and basic genetics of the bacteria, describes the molecular mechanisms of inheritance and genetic basis of inherited diseases, acquire skills necessary to perform experimental applications.
16) Learns the current literature information that will be useful in the professional sense within the scope of problem-based learning.
17) Uses information technologies effectively.
18) Acquires necessary language proficiency to follow the current literature and communicate with foreign colleagues.

Program Competencies-Learning Outcomes Relation

  Program Competencies
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
Learning Outcomes
1 High High Middle Low Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
2 High Low Middle Low Low Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
3 Middle No relation Low Low Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
4 Middle Middle Middle Middle Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
5 Middle No relation Middle Middle Middle Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
6 Middle No relation Low Middle Middle Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
7 Low Low Middle Middle Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
8 No relation No relation High High High No relation No relation Low Low No relation No relation No relation No relation No relation No relation No relation
9 Middle Middle Low No relation Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
10 Low Middle Middle High Middle Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
11 Middle Middle Middle Middle Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
12 High High Middle Middle Middle No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
13 No relation No relation No relation No relation No relation No relation No relation Middle Middle No relation No relation No relation No relation No relation No relation No relation
14 No relation No relation No relation No relation No relation No relation No relation High Middle No relation No relation No relation No relation No relation No relation No relation
15 High High Middle Middle Middle Low No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation
16 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation High High No relation No relation No relation No relation
17 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation High High High No relation No relation No relation
18 No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation No relation High No relation No relation High No relation

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Anatomy

Course Contents

Students will learn the structure of microorganism, genetic properties, reproductive patterns and their classification. It will cover the general characteristics of viruses, their classification, their replications and the genetic changes that take place in their structure. Mutations and carcinogens will elucidate and learn the effects of these factors on mutagenesis and carcinogenesis. Students will learn how to isolate DNA, RNA and protein from human lymphocytes. They will learn mutation screening, genotyping and PCR methods and will understand the basics of individualized treatment options. Students will be able to identify the developmental and structural changes of the embryo. They will learn the formation of germ dissections, the differentiation of germ layers, congenital disorders and their causes. "Relationships with values, attitudes and behaviors", they will learn about the interrelationships of interest, love, affinity, aggression, violence. We hope that this course will give insight into a subject that has developed rapidly during the last years. This is especially true when it comes to development of methods to study genomes of eukaryotic organisms but also our knowledge about the function and sequence organization of these genomes, genetic information flow, regulation of gene expression and gene technology. To give the essential facts of human development, clarifying the gross anatomic features along with the concepts in the basic science. Giving detail information on gametogenesis, formation of germ disc, derivatives of germ layers, establishment of body form and finally congenital malformations and their causes. Medical skills application covers practice of basic rules of first aid.

Weekly Schedule

1) Introduction to Medical Microbiology Amino group catabolism of amino acids and urea cycle cell cycle Sterilization and disinfection principles
2) Stem cells and basic concepts Carbon skeleton catabolism of amino acids Cell differentiation and apoptosis Oxidation of fatty acids Metabolism of bacteria
3) Metabolism of acylglycerols and sphingolipids Chromosomal Diseases-I Genetic characteristics of bacteria
4) Developmental theories Clinical and Molecular Cytogenetics Microbiology Lab 2: Morphology of Bacteria and staining properties
5) Classification of Fungi. Development III. Week Cancer genetics-I
6) Cancer genetics-II population genetics Fetal development The place of biotechnology in medicine
7) Fetal membranes and placenta Congenital malformations Research Methods in Medical Biology-II Structures and life cycles of arthropods
8) Biochemistry Lab : Ketone in blood/urine determination of bodies Microbiology Lab 8: Microorganisms control
9) IV. Course Committee Theoretical Exam Board evaluation

Recommended or Required Reading

1- Thompson & Thompson Genetics in Medicine, 2015

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice


Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade

60%

Contribution of Final Examination to Course Grade

40%

Total

100%

Language of Instruction

Turkish

Work Placement(s)

Not Required