Biological Fundamentals of Diseases

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Microbiology, Pathology, Genetics, Infectious disease, Pharmacology

Course Contents

Gram negative bacteria such as staphylococci, streptococci, Corynebacterium, listeria, Bacillus, characteristics of poststreptococcal diseases, gram-negative bacteria such as Brucella, Haemophilus, Bordetella, Neisseria and the like, and the microbiology of human microbiology, virulence factors and pathogenesis, Characteristics of anaerobic bacteria, properties of bacteria such as Riketsia, actinomycosis, nocardia and resistance mechanisms against antibiotics, nosocomial infections, diagnosis methods used in diagnosis of infections, rash infections, fever and unspecified fever. Acute and chronic inflammatory and chemical mediators, tissue repair, molecular basis of cancer, malignant and benign differentiation, carcinogens, tumor immunity and pathology to cancer, diagnosis of radiotherapy, basic principles, emergency situations, radionuclide protection and nuclear medicine, epidemiological and epidemiological studies of childhood cancer Genetic features include pathology, pediatrics oncology, radiation oncology and nuclear medicine. Information on single gene disorders, chromosomal diseases, prenatal diagnosis, cancer genetics and immunogenetics, genetic counseling and medical genetics. The main features of chemotrapoactive are various antibiotic properties, drugs used in tuberculosis treatment, drugs used in cancer treatment, antiseptics and disinfectants in pharmacology courses

Weekly Schedule

1) Basic Principles of Clinical Microbiology, Key features of Chemotherapeutics: pharmacokinetics and pharmacodynamics Approach, Immune response against bacteria, Beta lactam antibiotics: Penicillins, Human microbiota, Virulence and pathogenesis in bacteria, Introduction to the Clinic and Anamnesis, Staphylococci, Cephalosporins and other beta-lactam antibiotics, Tetracyclines and Chloramphenicol, Streptococci, Medical Microbiology practice 1: Flora , Gram positive aerobic non-spore bacilli, Introduction to the Clinic: Introduction to Semiology-1, Medical Microbiology practice 2: Microbiological examination of staphylococci, Poststreptococcal diseases, Gram positive aerobic bacilli with spores, Routine and specific diagnostic methods for the diagnosis of infectious diseases, Hemophilus and Bordetella
2) Neisseria, Francisella, Acute inflammation (vascular and cellular changes) , Nitroimidazoles, Polymyxins, Glycopeptide Antibiotics Drugs used in the treatment of tuberculosis and other mycobacterial infections, Fever and fever of unknown origin, Anaerobic bacteria, Chronic inflammation and chemical mediators, Mechanisms of action of antibiotics, Introduction to the Clinic: Head and neck examination, General characteristics of hospital infections, Mechanisms of resistance to antibiotics, Antimicrobial susceptibility tests, Medical Microbiology practice 3: Microbiological examination of streptococci, Macrolides, lincosamides and streptogramins, Fluoroquinolones , SARS-Coronavirus 2 disease, Medical Microbiology practice 4: Microbiological examination of Neisseria and hemophilus / Medical Pathology practice 1, Intrauterine infections, Tissue Repair, Nuclear medicine and principles of radiation protection, Medical Microbiology practice 5: Microbiological examination of aerobic sporeless and non-spore-forming bacilli and anaerobic bacteria / Medical Pathology practice 2
3) Sulfonamides and co-trimaxazol, Aminoglycosides, Chromosomal diseases, Single gene diseases Introduction to the Clinic: Cardiovascular system examination, Medical photography and video shooting, Neoplasia I (definitions, benign-malignant distinction), Antiseptics and disinfectants Drugs used in cancer treatment, Introduction to the Clinic: Respiratory system examination, Non-Mendelian inheritance, Neoplasia II (grading, staging, epidemiology), Role of pathology in cancer diagnosis, Epidemiological and genetic features and biology of childhood cancers, Introduction to the Clinic: Abdominal examination, Prenatal diagnosis , Molecular bases of cancer – I , Treatment principles of childhood cancers , Medical Microbiology practice 6: Antibiogram production and evaluation, Cancer genetics and Immunogenetics, Molecular bases of cancer – II , Cancer etiology-Carcinogenic agents, Genetic Counseling, Stem cells; Adult stem cells, Introduction to the Clinic: Nervous system examination
4) Introduction to the Clinic: Patient Safety-1 (group A), Tumor immunity, Clinical features of neoplasms, Medical Pathology practice 3 Introduction to the Clinic: Patient Safety-2 (group B), Medical Microbiology Lab. Compensation
5) Medical Pathology Lab. Exam; Freelance Study (Exam Preparation for End of Board); Medical Microbiology Lab. Exam; I. Lecture Committee Theoretical Exam; Board Evaluation.
6) Freelance Study (Exam Preparation for End of Board); Medical Pathology Lab. Exam; Freelance Study (Exam Preparation for End of Board); Medical Microbiology Lab. Exam; I. Lecture Committee Theoretical Exam; Board Evaluation.
7) Exam Preparation for End of Board; Medical Pathology Lab. Exam; Freelance Study (Exam Preparation for End of Board); Medical Microbiology Lab. Exam; I. Lecture Committee Theoretical Exam; Board Evaluation.
8) ...

Recommended or Required Reading

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice
5) Demonstration
6) Modelling
7) Group Study
8) Simulation
9) Case Study
10) Lab / Workshop
11) Self Study
12) Problem Solving

Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade	60%
Contribution of Final Examination to Course Grade	40%
Total	100%

Language of Instruction

Turkish

Work Placement(s)

Not Required