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Course Unit Title Course Unit Code Type of Course Unit Level of Course Unit Year of Study Semester ECTS Credits
Biochemical Reaction Engineering MKM509 Elective Master's degree 1 Fall 8

Name of Lecturer(s)

Associate Prof. Dr. Nurcan KAPUCU

Learning Outcomes of the Course Unit

1) Recognize the principles concepts biochemical reaction engineering and bioprocesses
2) Solve the problems related to enzyme kinetic
3) Describe the immobilized cell and enzyme systems, and transport phenomena
4) Explain the batch, continuous and semi-batch growth kinetics
5) Solve the problems related to batch, fed-batch, continuous, recycled, and combined bioreactor
6) Identify the metabolic control mecanisms in livings and microbial stoichiometry

Program Competencies-Learning Outcomes Relation

  Program Competencies
1 2 3
Learning Outcomes
1 Low No relation No relation
2 Middle No relation No relation
3 Low No relation No relation
4 Middle No relation No relation
5 Middle No relation No relation
6 Low No relation No relation

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Biochemistry, biotechnology

Course Contents

Overview of Biochemical Reaction Engineering / Cell Types and Structures/ Metabolism, Metabolic Pathways, Metabolic Regulation / Enzymes and Enzyme Kinetic / Immobilized Enzymes and Immobilized Cell Systems / Cell Growth Kinetic: Batch and Continuous Cultivation of Cell, Generalized cell, substrate and product balances / Bioreactors : Operations, Batch, Fed-batch, Continuous, Recycled, and Combined Systems / Transport Phenomena in Bioprocesses

Recommended or Required Reading

1- Bailey, J.E. and Ollis, D.F.,“Biochemical Engineering Fundamentals”, McGRAW-Hill Ed., 1986.
2- Shuler, M.L. and Kargı, F. Bioprocess Engineering: Basic conceppts, Second edition, Prentice Hall Inc., 2002.
3- Atkinson B., and Mavituna, F., Biochemical Engineering and Biotechnology Handbook, Second Edition, Stockton Press, 1991
4- Blanch, H.W., Clark, D.S. Biochemical Engineering, Marcel Dekker, Inc., New York, 1996.
5- Aiba S., Humphrey, A.E., Millis N.F., Biochemical Engineering Second Edition, Academic Press, Inc., Ney York, 1973
6- Lee, J.M., Biochemical Engineering, Prentice Hall, New Jersey, 1992.
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Planned Learning Activities and Teaching Methods

1) Lecture
2) Lecture
3) Discussion
4) Discussion
5) Demonstration
6) Demonstration
7) Group Study
8) Group Study
9) Problem Solving
10) Problem Solving


Assessment Methods and Criteria

 

Number

Percentage

Contribution of Quiz to Course Grade

4

50%

Contribution of Final Examination to Course Grade

1

50%

Total

100%

Language of Instruction

Turkish

Work Placement(s)

Not Required