Downstream Processing of Bioproducts
Chemical Engineering
Institute of Natural and Applied Sciences
Second Cycle (Master's Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Downstream Processing of Bioproducts | MKM508 | Elective | Master's degree | 1 | Spring | 8 |
Name of Lecturer(s)
Associate Prof. Dr. Nurcan KAPUCU
Learning Outcomes of the Course Unit
1) Acquire the knowledge about recovery, separation and purification processes of bio-products
2) Acquire the knowledge about removal of insolubles by filtration, centrifugation
3) Acquire the knowledge about cell disruption methods
4) Acquire the knowledge about isolation of products by adsorption and extraction
5) Investigate the purification processes such as chromatography, electrophoresis, dialysis and membrane processes
6) Acquire the knowledge about drying and crystallization methods
7) Acquire the experience of studying individually by giving a project
8) Provide necessary experience for scientific criticism
Program Competencies-Learning Outcomes Relation
| Program Competencies | ||||
| 1 | 2 | 3 | ||
| Learning Outcomes | ||||
| 1 | Middle | No relation | No relation | |
| 2 | Low | No relation | No relation | |
| 3 | Low | No relation | No relation | |
| 4 | Low | No relation | No relation | |
| 5 | Low | No relation | No relation | |
| 6 | Low | No relation | No relation | |
| 7 | Low | No relation | No relation | |
| 8 | Low | No relation | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
None
Course Contents
Principles of bioseperation processes / Seperation of insolubles: Filtration, centrifugation, coagulation, flocculation, flotation, sedimentation / Cell Disruption : Mechanic and non-mechanic methods / Initial isolation and concentration of products : Evaporation, extraction, adsorption, precipitation / Purification : chromatography, electrophoresis, dialysis and membrane separations, ultrafiltration, microfiltration / Polishing : Crystallization, drying
Recommended or Required Reading
1- Garcia A.A., Bonen M.R., Ramirez Vick J., Sadaha M., Vuppa A., Bioseparation Process Science, Blackwell.
2- Sivasankar, B., 2005. Bioseperations : Principles and Techniques, Prentice Hall.
3- Harrison, R.G., Todd, P.W., Rudge, S.R., Petrides, D., 2003. Bioseperations Science and Engineering, Oxford University Press.
4- Belter, P.A., E. L. Cussler, and W-S. Hu, 1988, Bioseparations : Downstream Processing for
Biotechnology, Wiley-Interscience, New York.
5- Hamel, J.F., Sikdar, S.K., Huner, J.B., 1989. Downstream Processing and Bioseparation: Recovery and Purification of Biological Products, American Chemical Society,
Planned Learning Activities and Teaching Methods
1) Lecture
2) Question-Answer
3) Discussion
Assessment Methods and Criteria
Number |
Percentage |
|
|---|---|---|
Contribution of Presentation/Seminar to Course Grade |
4 |
50% |
Contribution of Final Examination to Course Grade |
1 |
50% |
Total |
100% |
|
Language of Instruction
Turkish
Work Placement(s)
Not Required