| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Bioreactor Design | MKM533 | Elective | Master's degree | 1 | Fall | 8 |
Name of Lecturer(s)
Associate Prof. Dr. Başar UYAR
Learning Outcomes of the Course Unit
1) Describe the components of bioreactor design process
2) Design biological reactors by combining engineering calculations with fundamental sciences such as biology and chemistry
3) Discuss the validity and applicability of different bioreactor designs for different biological systems
4) Compare traditional and novel bioreactor types
5) Analyze and interpret the data collected from bioreactor instrumentation.
Program Competencies-Learning Outcomes Relation
| Program Competencies | ||||
| 1 | 2 | 3 | ||
| Learning Outcomes | ||||
| 1 | No relation | No relation | Middle | |
| 2 | No relation | No relation | High | |
| 3 | Low | Low | High | |
| 4 | Low | No relation | Middle | |
| 5 | No relation | Low | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Biotechnology
Course Contents
Unique features of bioreactors / Principles of bioreactor design / Scale up and scale down in bioreactors/ Bioreactor design for different biological systems / Design of specialized bioreactors
Weekly Schedule
1) Basic concepts of biological processes and bioreactors2) Limitations, considerations and parameters to be used in bioreactor design
3) Bioreactor design aspects I (Construction material, geometry, configuration of main components)
4) Bioreactor design aspects II (Aeration, agitation, heat and mass transfer, foaming, power consumption)
5) Bioreactor design aspects III (Modes of bioreactor operation such as batch, fed-batch, continuous, multistage, recycle)
6) Bioreactor design aspects IV (Bioreactor types: traditional (CSTR, bubble column, air-lift, plug flow, packed bed, solid state surface...) and novel bioreactor types
7) Scale up and scale down in bioreactors
8) Mid Term Exam / Assessment
9) Photobioreactor design
10) Immobilized bioreactor design
11) Anaerobic bioreactor design
12) Bioreactor design for microbial cell cultures
13) Bioreactor design for plant cell cultures
14) Bioreactor design for insect and mammalian cell cultures
15) Recombinant cell bioreactor design and operations
16) Final Exam and assessment
Recommended or Required Reading
Planned Learning Activities and Teaching Methods
1) Lecture
2) Question-Answer
3) Discussion
4) Self Study
5) Problem Solving
Assessment Methods and Criteria
Contribution of Midterm Examination to Course Grade |
50% |
|---|---|
Contribution of Final Examination to Course Grade |
50% |
Total |
100% |
Language of Instruction
Turkish
Work Placement(s)
Not Required