Porphyrins and Disorders of Porphyrin Metabolism Hemoglobin, İron, Bilirubin
Biochemistry
Institute of Health Sciences
Third Cycle (Doctorate Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Porphyrins and Disorders of Porphyrin Metabolism Hemoglobin, İron, Bilirubin | BYK743 | Elective | Doctorate degree | 2 | Fall | 3 |
Name of Lecturer(s)
Prof. Dr. Meltem Özlen DİLLİOĞLUGİL
Learning Outcomes of the Course Unit
1) Understand the structures, functions, classification, digestion, metabolism, and metabolic integrity of biological molecules such as porphyrins.
2) Describe the diseases that develop due to the disorders seen in the metabolic pathways.
3) Learn bilirubin, ammonia, urea and uric acid metabolisms.
Program Competencies-Learning Outcomes Relation
| Program Competencies | ||||||
| 1 | 2 | 3 | 4 | 5 | ||
| Learning Outcomes | ||||||
| 1 | High | High | High | No relation | No relation | |
| 2 | High | High | Middle | No relation | No relation | |
| 3 | Middle | Middle | Middle | No relation | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Not Required
Course Contents
Disorders of porphyrin and porphyrin metabolism Hemoglobin, iron and bilirubin Biochemical view on hepatobiliary system
Weekly Schedule
1) Properties of porphyrins, porphyrins, function.2) oxygen-binding proteins; hemoglobin and myoglobin
3) Hemoglobin subunits and their effects on binding
4) other proteins involved in oxygen transport, the role of hemoglobin in the transport of hydrogen and carbon dioxide
5) Hem biosynthesis in the body
6) Regulation and destruction of Hem in the body
7) Diseases caused by deterioration of hemoglobin metabolism
8) Jaundice and porphyria, diseases caused by abnormal hemoglobin, hemoglobinopathies
9) MID-TERM
10) Structure and compounds of hemoglobin
11) Hemoglobin biosynthesis and hemoglobin breakdown
12) Bilirubin metabolism
13) Classification of hyperbilirubinemia
14) Iron metabolism
15) Anemia due to lack of iron
16) SEMESTRE FINAL EXAM
Recommended or Required Reading
Planned Learning Activities and Teaching Methods
Assessment Methods and Criteria
Contribution of Semester Studies to Course Grade |
40% |
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Contribution of Final Examination to Course Grade |
60% |
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Total | 100% | |||||||||||
Language of Instruction
Turkish
Work Placement(s)
Not Required