Advanced Cellular Engineering
Stem Cell and Tissue Regeneration
Institute of Health Sciences
Third Cycle (Doctorate Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Advanced Cellular Engineering | KHT609 | Elective | Doctorate degree | 1 | Fall | 6 |
Name of Lecturer(s)
Associate Prof. Dr. Gökhan DURUKSU
Learning Outcomes of the Course Unit
1) Gaining the knowledge on cell engineering
2) Recognizing the importance of cell-matrix relation in stem cell biology
3) Planning the relevent experimental studies with cell engineering
4) Gaining critical view on stem cell improvement by recombination
5) Planning the relevent experimental studies with stem cells
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||||
| 1 | 2 | 3 | 4 | 5 | 6 | ||
| Learning Outcomes | |||||||
| 1 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 2 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 3 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 4 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 5 | No relation | No relation | No relation | No relation | No relation | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Recent Studies on Stem Cell and Regenerative Biology
Course Contents
This course basically will examine the feasibility of new approaches for the modification of cellular function in progenitor cells and adult stem cells such as gene expression, protein processing, secretion, glycosylation, immortalization, proliferation, and apoptosis in mammalian systems. The methodologies for improving cellular properties of stem cells used in gene and cell therapies, tissue engineering and in the production of biopharmaceuticals will be discussed. In the scope of this course, the cellular mechanisms underlying in vitro physiological activity and productivity will be focused on cell-material interaction, nano-scale structures and three dimensional culture systems.
Weekly Schedule
1) Introduction to progenitor cells and adult stem cells2) Introduction to progenitor cells and adult stem cells
3) Cell proliferation, apoptosis and other cellular events
4) Cell proliferation, apoptosis and other cellular events
5) Gen expression, protein synthesis and secretion in mammalian cells
6) Glycoproteins and glycolysis
7) Immortality
8) Mid-term exam
9) Bio-pharmaceutics and gene therapies
10) Bio-pharmaceutics and gene therapies
11) Cell and tissue engineering
12) Cell and tissue engineering
13) Improvement of cellular characteristics of stem cells
14) Improvement of cellular characteristics of stem cells
15) 2D- and 3D-culture systems
16) Final exam
Recommended or Required Reading
Planned Learning Activities and Teaching Methods
1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice
5) Self Study
Assessment Methods and Criteria
Contribution of Semester Studies to Course Grade |
50% |
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Contribution of Final Examination to Course Grade |
50% |
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Total | 100% | |||||||||||
Language of Instruction
Turkish
Work Placement(s)
Not Required