Pluripotent Stem Cell
Stem Cell and Tissue Regeneration
Institute of Health Sciences
Third Cycle (Doctorate Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Pluripotent Stem Cell | KHT604 | Compulsory | Doctorate degree | 1 | Fall | 6 |
Name of Lecturer(s)
Prof. Dr. Yusufhan YAZIR
Learning Outcomes of the Course Unit
1) Knows the definition, classification and sources of stem cells.
2) Have knowledge about human embryonic stem cells and induced pluripotent stem cells.
3) Have knowledge about isolation and culture conditions of embryonic stem cells.
4) Have knowledge about in vitro differentiation of pluripotent stem cells.
5) Have knowledge about IPS technologies and IPS creation.
6) Have information about VSEL.
7) Have knowledge about the use of pluripotent stem cells in disease modeling.
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||||
| 1 | 2 | 3 | 4 | 5 | 6 | ||
| Learning Outcomes | |||||||
| 1 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 2 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 3 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 4 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 5 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 6 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 7 | No relation | No relation | No relation | No relation | No relation | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Not Required
Course Contents
Properties and classification of pluripotent stem cells, embryonic stem cells, induced pluripotent stem cells and pluripotent stem cells in clinical practice
Weekly Schedule
1) Stem Cells; definition, classification and sources2) Human embryonic stem cells and induced pluripotent stem cells
3) Formation and potential of pluripotent stem cells on organogenesis
4) Embryonic stem cell isolation and culture conditions
5) Morphology of undifferentiated embryonic stem cells under suspension and dynamic culture conditions
6) In vitro differentiation of pluripotent stem cells: embryoid body
7) In vivo differentiation of pluripotent stem cells: formation of teratomas
8) Midterm
9) IPS
10) IPS technologies
11) Creating an IPS
12) VSEL
13) Use of pluripotent stem cells in disease modeling
14) Analysis of pluripotent stem cells by immunostaining
15) Pluripotent stem cells in stem cell therapy and ethical approaches
16) Final exam
Recommended or Required Reading
1- Kök Hücre. Prof.Dr. Alp CAN, 2013. Akademisyen Kitabevi, ISBN:9786054649433
2- Essentials of stem cell biology, Editör: Robert Lanza, John Gearhart, Brigid Hogan, Douglas Melton, Roger Pedersen, E. Donnall Thomas, James A. Thomson. 2006 Elsevier Academic Press
Planned Learning Activities and Teaching Methods
1) Lecture
2) Lecture
3) Question-Answer
4) Question-Answer
5) Question-Answer
6) Discussion
7) Discussion
8) Discussion
Assessment Methods and Criteria
Contribution of Midterm Examination to Course Grade |
40% |
|---|---|
Contribution of Final Examination to Course Grade |
60% |
Total |
100% |
Language of Instruction
Turkish
Work Placement(s)
Not Required