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Course Unit Title Course Unit Code Type of Course Unit Level of Course Unit Year of Study Semester ECTS Credits
Stem Cells and Photodynamic Therapy KHT653 Elective Doctorate degree 1 Fall 5

Name of Lecturer(s)

Prof. Dr. Yusufhan YAZIR
Associate Prof. Dr. Gülçin GACAR
Associate Prof. Dr. MELTEM GÖKSEL ŞAHIN

Learning Outcomes of the Course Unit

1) Students who have successfully completed this course; • May have knowledge about stem cell identification, microenvironment and properties. • The stem cell will count by describing its hand and its markers. • Cancer will be able to identify the basic properties of stem cells. • Describe the concept of stem cell microenvironment. • Will be able to interpret developments about photodynamic therapy by using stem cells from the literature.

Program Competencies-Learning Outcomes Relation

  Program Competencies
1 2 3 4 5 6
Learning Outcomes
1 High High High High High High

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Not Required

Course Contents

Introduction and history of stem cell biology, definition of stem cells, cancer stem cells, stem cell microcirculation, advantages and disadvantages of stem cells and their use, development and clinical application of photodynamic therapy.

Weekly Schedule

1) Identification of stem cells and basic concepts in stem cell biology
2) The role of stem cells in cancer identification and cancer formation
3) Cancer stem cells, markers and signaling pathways
4) Identification, markers, signaling pathways of stem cells in cancer
5) Overview of cancer treatment methods
6) Approaches for targeted cancer therapy
7) Midterm
8) Definition and history of photodynamic therapy.
9) Description and history of 1st, 2nd and 3rd generation Photodynamic therapy agents
10) Working mechanism of photodynamic therapy agents (Singlet oxygen production)
11) Types of photodynamic therapy agents and phthalocyanines
12) Chemical analysis applied to photodynamic therapy agents
13) Targeted Photodynamic therapy agent design
14) Examples of successful applications of photodynamic therapy
15) Examples of successful applications of photodynamic therapy
16) Final Exam

Recommended or Required Reading

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Question-Answer
4) Question-Answer
5) Question-Answer
6) Question-Answer
7) Discussion
8) Discussion
9) Discussion
10) Discussion
11) Discussion
12) Discussion
13) Brain Storming
14) Brain Storming
15) Brain Storming
16) Brain Storming
17) Brain Storming
18) Self Study


Assessment Methods and Criteria

Contribution of Midterm Examination to Course Grade

50%

Contribution of Final Examination to Course Grade

50%

Total

100%

Language of Instruction

Turkish

Work Placement(s)

Not Required