Stem Cells In Hereditary Diseases and Experimental Models
Stem Cell and Tissue Regeneration
Institute of Health Sciences
Third Cycle (Doctorate Degree)
| Course Unit Title | Course Unit Code | Type of Course Unit | Level of Course Unit | Year of Study | Semester | ECTS Credits |
|---|---|---|---|---|---|---|
| Stem Cells In Hereditary Diseases and Experimental Models | KHT654 | Elective | Doctorate degree | 1 | Fall | 5 |
Name of Lecturer(s)
Associate Prof. Dr. Gökhan DURUKSU
Assistant Prof. Dr. Zehra Seda HALBUTOĞULLARI
Learning Outcomes of the Course Unit
1) Learning of hereditary disease types and molecular mechanisms.
2) Learning of stem cell applications in hereditary blood, heart and diabet diseases.
3) Gain information about gene therapy, stem cell and cellular therapy in hereditary diseases.
4) Learning the basics of creating an experimental model
Program Competencies-Learning Outcomes Relation
| Program Competencies | |||||||
| 1 | 2 | 3 | 4 | 5 | 6 | ||
| Learning Outcomes | |||||||
| 1 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 2 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 3 | No relation | No relation | No relation | No relation | No relation | No relation | |
| 4 | No relation | No relation | No relation | No relation | No relation | No relation | |
Mode of Delivery
Face to Face
Prerequisites and Co-Requisites
None
Recommended Optional Programme Components
Advanced Cell and Stem Cell Biology
Course Contents
Hereditary diseases, disease modeling, stem cell and gene therapy applications.
Weekly Schedule
1) Hereditary diseases and their classification2) Stem cell applications in experimental models
3) Immunodeficiency diseases and stem cell approaches in treatment
4) Hemoglobinopathies and stem cell treatments
5) Genetic based stem cell applications in cardiovascular regeneration
6) Diabetes mellitus, disease models, stem cell treatment approaches
7) Gene therapies and risks in hereditary diseases and Crispr-Cas9
8) Quiz
9) Muscular dystrophies, disease models and stem cell therapy approaches
10) Hereditary metabolic diseases and disease models
11) Stem cell transplantation in lysosomal storage diseases
12) Stem cell transplantation in peroxisomal diseases
13) Stem cell transplantation in neurometabolic and neurodegenerative diseases
14) Cancer and stem cell treatment approaches
15) Evaluation of hereditary diseases and experimental models / stem cell and gene therapy applications
16) Final exam
Recommended or Required Reading
1- Thompson & Thompson Genetics in Medicine. Ed. Roderick R. McInnes, Huntington F. Willard, Robert L. Nussbaum, 2015, Elsevier, ISBN: 978-1-437-70696-3
2- Stem Cells & Regenerative Medicine: From Molecular Embryology to Tissue Engineering. Ed. Krishnarao Appasani, Raghu K. Appasani, 2010, Humana Press, Heidelberg
3- Lewin's GENES X. Ed. Jocelyn Krebs, Elliott Goldstein, Stephen Kilpatrick, 2009, Jones & Bartlett Publishers. ISBN-13: 978-0-7637-6632-0
Planned Learning Activities and Teaching Methods
1) Lecture
2) Lecture
3) Question-Answer
4) Question-Answer
5) Discussion
6) Discussion
7) Brain Storming
8) Brain Storming
Assessment Methods and Criteria
Contribution of Semester Studies to Course Grade |
60% |
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Contribution of Final Examination to Course Grade |
40% |
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Total | 100% | ||||||||||||||
Language of Instruction
Turkish
Work Placement(s)
Not Required