>
Course Unit Title Course Unit Code Type of Course Unit Level of Course Unit Year of Study Semester ECTS Credits
Cell Cycle and Control Mechanisms KHT607 Elective Doctorate degree 2 Fall 5

Name of Lecturer(s)

Prof. Dr. Yusufhan YAZIR
Associate Prof. Dr. Gökhan DURUKSU
Associate Prof. Dr. Gülçin GACAR

Learning Outcomes of the Course Unit

1) Knows and understands the basic concepts and mechanisms of cell cycle .
2) Understands, analyzes and evaluates cell-cycle and cell cycle control system.
3) Explain basic mechanisms of DNA synthesis.
4) Knows and understands control of proliferation and growth.
5) Knows and understands the basic concepts and mechanisms of Apoptosis.
6) Knows and understands the DNA damage response.
7) Have knowledge about the cell cycle in cancer, and uses this information in the research for clinical practice.
8) Explains cell cycle defects .
9) Knows gene mutations and follows the recent advances.
10) Knows and explains the tissue-specificity of cancer.
11) Knows and understands the basic concepts and mechanisms of cell growth and survival in tumors.
12) Understands, analyzes and evaluates telomeres and the structural instability of chromosomes.
13) Have knowledge about instability of chromosome number and follows the recent advances.
14) Knows and understands about stopping cancer progression and cancer-related mechanisms .

Program Competencies-Learning Outcomes Relation

  Program Competencies
1 2 3 4 5 6
Learning Outcomes
1 No relation No relation No relation No relation No relation No relation
2 No relation No relation No relation No relation No relation No relation
3 No relation No relation No relation No relation No relation No relation
4 No relation No relation No relation No relation No relation No relation
5 No relation No relation No relation No relation No relation No relation
6 No relation No relation No relation No relation No relation No relation
7 No relation No relation No relation No relation No relation No relation
8 No relation No relation No relation No relation No relation No relation
9 No relation No relation No relation No relation No relation No relation
10 No relation No relation No relation No relation No relation No relation
11 No relation No relation No relation No relation No relation No relation
12 No relation No relation No relation No relation No relation No relation
13 No relation No relation No relation No relation No relation No relation
14 No relation No relation No relation No relation No relation No relation

Mode of Delivery

Face to Face

Prerequisites and Co-Requisites

None

Recommended Optional Programme Components

Not Required

Course Contents

The Cell Cycle; Cell Cycle Analysis; The Cell Cycle Control System; Basic Mechanisms of DNA Synthesis; Control of Proliferation And Growth; Apoptosis; The DNA Damage Response; The Cell Cycle In Cancer; Cell Cycle Defects; Gene Mutations; Tissue Specificity In Cancer; Cell Growth and Survival In Tumors; Telomeres and The Structural Instability of Chromosomes; Instability of Chromosome Number; Cancer Progression; Stopping Cancer

Weekly Schedule

1) The Cell Cycle, Cell Cycle Analysis
2) The Cell Cycle Control System
3) Basic Mechanisms of DNA Synthesis
4) Control of Proliferation And Growth
5) Apoptosis
6) The DNA Damage Response
7) The Cell Cycle In Cancer
8) Midterm Examination/Assessment
9) Cell Cycle Defects
10) Gene Mutations
11) Tissue Specificity In Cancer
12) Cell Growth and Survival In Tumors
13) Telomeres and The Structural Instability of Chromosomes
14) Instability of Chromosome Number
15) Cancer Progression, Stopping Cancer
16) Final Examination

Recommended or Required Reading

1- The Cell Cycle, Principles of Control. David O Morgan.

Planned Learning Activities and Teaching Methods

1) Lecture
2) Question-Answer
3) Discussion
4) Drill and Practice
5) Demonstration
6) Modelling
7) Group Study
8) Brain Storming
9) Lab / Workshop
10) Self Study
11) Problem Solving


Assessment Methods and Criteria

Contribution of Semester Studies to Course Grade

40%

 

Number

Percentage

Semester Studies

Midterm Examination

1

50%

Practices

1

20%

Laboratory

1

30%

 

Contribution of Final Examination to Course Grade

60%

Total

100%

Language of Instruction

Turkish

Work Placement(s)

Not Required